Barnette's Conjecture: Every 3-connected cubic planar bipartite graph is Hamiltonian.
It is known that this is not true if you remove the "bipartite" condition, but the smallest 3-connected cubic planar graph which is not Hamiltonian has 38 vertices.
Holton, Manvel, and McKay  proved (using computers) that all graphs having fewer than 66 vertices satisfy the conjecture.
 D. Holton, B. Manvel, B. D. McKay, Hamiltonian cycles in cubic 3-connected bipartite planar graphs, J. Combin. Theory Ser. B 38 (1985) 279-297.
Send comments to Bojan.Mohar@uni-lj.si
A communication by Robert Aldred, Gunnar Brinkmann, and Brendan McKay (December 2002):
A paper of Holton, Manvel and McKay (JCT-B 38(1985)279-297) proved Barnette's conjecture for up to 64 vertices, inclusive. This is to announce that the conjecture remains true up to 84 vertices, inclusive. The method used was the same as in the 1985 paper, but took advantage of two developments. One was the new program plantri (Brinkmann and McKay, to be published) which can generate the required graphs without isomorphs at more than 100,000 per second. The other was the advance in computers. Total cpu time was about 3 years, almost all of it taken in finding hamiltonian cycles. Specifically, for all 3-connected cubic planar bipartite graphs up to 60 vertices, and those up to 64 vertices not having a 4-face adjacent to two others, we found a hamiltonian cycle using x and avoiding y for each pair of edges x and y. There are over 10^10 such graphs. By a theorem of Kelman's, one can build a counterexample to Barnette's conjecture when one has a 3-connected cubic planar bipartite graph with this property: for some two edges x and y on the same face, there is no hamiltonian cycle that uses x and avoids y. We did not find any such graph even where x and y are not required to be on the same face. Perhaps the path to finding a counterexample is to strengthen Kelman's method to some more complicated condition involving 3 or more edges, as then it is more likely to fail on a smaller size.
There is another conjecture of Barnette: Planar, 3-connected, faces only of size 3,4,5,6 implies Hamiltonian. Brendan and Gunnar checked it up to 250 vertices.