Domov > Obvestila > Primož Ziherl: Tension-based model of epithelial tissues

Primož Ziherl: Tension-based model of epithelial tissues

Datum objave: 22. 3. 2018
Vir: Ponedeljkov fizikalni kolokvij
Ponedeljek, 26. 3. 2018 ob 16.15 v predavalnici F1, UL FMF, Jadranska 19, Ljubljana

Tension-based model of epithelial tissues

 

Primož Ziherl

Faculty of Mathematics and Physics, University of Ljubljana

Jožef Stefan Institute

 

Many layered biological tissues are characterized by strikingly regular patterns and formations, which may be interpreted using mechanistic theories. We review selected results obtained using a tension-based vertex model implemented in both 2D and 3D. We present a theory of the shape of epithelial folds typical, e.g., for the gastrointestinal tract of certain simple animals, and an analysis of the formation of ventral furrow in the Drosophila embryo. Also discussed is the structure of a fluidized single-cell-thick epithelium and its viscoelastic response. Finally, we turn to the shape of organoids viewed as closed epithelial shells.

 

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