Bioelectromagnetism

Regular enrolement

Introduction: electric, magnetic and electromagnetic effect in live beings and humans
Basics of electrophysiological effects: neural and muscle cells, electric effects on cell membrane, electrophysiological measurements on the cellular level, cells in brain, neurons and heart
Bioelectrical source in humans, tissue a conductor, measurements, simulations, modeling: dipole, volume source, volume conductor, source – field, forward and inverse problem (example of heart), double-domain model, effect of aniosotropy
Bioelectica and biomagnetic measurements: electrodes on volumetric conductor, measurements of biomelectrical potential differences, biomagnetic fields, SQUID magnetometer: one-channel and multi-channel versions, electromagnetic safety, ECG, MCG, EEG, MEG, EMG measurements – clinical applications, basic diagnosis from ECG and MCG measurements
Electric and magnetic signals from other electro-active organs: eye, digestive system, lungs
Electrical and magnetic stimulation: electric stimulation of the heart, heart defibrillation, functional nerve stimulation
Measurements of electric and magnetic properties of neurons: impedence volumetric methods, blood flow in extremities, measurements of the magnetic lung pollution, importance of the magnetic indicators in digestive system

• Jaakko Malmivuo, Robert Plonsey, Plonsey Malmivuo, Bioelectromagnetism: Principles and Applications of Bioelectric and Biomagnetic Fields, Oxford University Press; (August 1995), 512 pp, ISBN: 0195058232

Students learn about the basics of electrophysiological activities of organs (or parts of organs) in human and other live beings
Competences: Understanding of organ electrophysiological activities. Ability to physically describe electrophysiological activity of different organs. Modeling of the electromagnetic effects. Ability to solve forward and inverse problems. Critical understanding of electro- and magneto-physicological measurements and protection against external fields. Comparison and analysis with other diagnostic approaches.

Knowledge and understanding:
Understanding of the fundamental electromagnetic concepts in humans. Being able to quantify and analyze electrophysiological measurements. Being able to model the process and connect to other diagnostic procedures.
Application:
Use of electromagnetic activity in humans as supplements to other diagnostic methods.
Reflection:
Critical evaluation of the electrophysiologic measurements. Ability to connect the knowledge to other imaging methods.
Transferable skills:
Application of the mathematical modeling skils to the electrophysiological problems. Ability to analyze the data. Ability to effectively communicate with the physicians.

Lectures, seminars, consultations.

Oral exam
Written exam (problem solving)
grading: 5 (fail), 6-10 (pass) (according to the Statute of UL)

1. V. Jazbinšek, R. Hren, G. Stroink, M. B. Horáček, Z. Trontelj, Value and limitations of an inverse solution for two equivalent dipoles in localising dual accessory pathways, Med. biol. eng. comput., vol. 41, no. 2, str. 133-140, 2003.
2. R. Hren, G. Stroink, Noninvasive characterisation of multiple ventricular events using electrocardiographic imaging, Med. Biol. Eng. Comput., vol. 39, pp. 447-454, 2001.
3. J. Pirnat, Z. Trontelj. Correlation-based method for improvement of NQR signals utilizing signal shape information. Appl. magn. reson., 2004, vol. 27, no. 1-2, str. 343-357.