Prof. Gerald Kneller: Structural and dynamical heterogeneity of protein dynamics
Povzetek:
Prof. Gerald Kneller, Centre de Biophysique Moléculaire, CNRS Orléans & Synchrotron Soleil, St.-Aubin, France
Structural and dynamical heterogeneity of protein dynamics
The dynamics of proteins is known to exhibit a broad spectrum of time scales and amplitudes, which are caused by coupled motions within the molecule, but also by coupling with the solvent. In this talk a simple model is presented which captures the heterogeneity of atomic motions in space and time astonishingly well. The relations to established models for protein dynamics, such as normal and Brownian mode analysis and fractional Brownian dynamics, are discussed and implications for the interpretation of experimental data and computer simulations are emphasized.
